{"text_format":"3","workbook":"xls","n_sheets":1,"sheets":["rno"],"read":"whole","date_system":"1900","formulas":"cached_only"}

{"sheet":"rno","index":0,"n_rows":56,"n_cols":11,"rows_kept":56,"merged":[[0,0,0,10],[1,0,1,10],[2,0,2,10],[3,0,3,10],[4,0,4,10],[5,0,5,10],[6,0,6,10],[7,0,7,10],[8,0,8,10],[9,0,9,10],[10,0,10,10],[11,0,11,10]],"flags":["formulas_cached_only"]}
["#Column \"PathwayID\" stands for Pathway identifiers used in KEGG"]
["#Column \"Definition\" stands for the definition of the PathwayID"]
["#Column \"OriginalWebSite\"stands for The map's website,the nodes with red frame and red symbol are associated with the DE genes, green nodes have no significance"]
["#Column \"p-value\" "]
["        \"Fisher-Pvalue\" stands for the enrichment p-value of the PathwayID used Fisher's exact test"]
["#Column \"SelectionCounts\" stands for the Count of the DE genes' entities directly associated with the listed PathwayID"]
["#Column \"SelectionSize\" stands for the total number of the DE genes' entities"]
["#Column \"Count\" stands for the count of the chosen background population genes' entities associated with the listed PathwayID"]
["#Column \"Size\" stands for the total number of chosen background population genes' entities"]
["#Column \"FDR\" stands for the false discovery rate of the PathwayID"]
["#Column \"Enrichment_Score\" stands for the Enrichment Score value of the PathwayID, it equals \"-log10(Pvalue)\""]
["#Column \"GENES\" stands for the DE genes associated with the PathwayID"]
[]
["PathwayID","Definition","OriginalWebSite","Fisher-Pvalue","SelectionCounts","SelectionSize","Count","Size","FDR","Enrichment_Score","Genes"]
["rno03320","PPAR signaling pathway - Rattus norvegicus (rat)","http://www.genome.jp/kegg-bin/show_pathway?rno03320+83522+113976+140638+25428+171142+79131+289481+58852+140914+362282+25747+246074+50522",4.9895820000000006e-05,13,350,78,7583,0.01382114,4.3019359999999995,"ACOX3//ACSL4//APOA5//CYP7A1//EHHADH//FABP3//GK2//NR1H3//OLR1//PCK1//PPARA//SCD1//UBC"]
["rno00620","Pyruvate metabolism - Rattus norvegicus (rat)","http://www.genome.jp/kegg-bin/show_pathway?rno00620+298079+65183+64040+24533+24534+29634+24551+362282+24651",0.00017371120000000002,9,350,45,7583,0.024059,3.760172,"ALDH1B1//ALDH3A2//ALDH9A1//LDHA//LDHB//LDHC//MDH1//PCK1//PKLR"]
["rno00640","Propanoate metabolism - Rattus norvegicus (rat)","http://www.genome.jp/kegg-bin/show_pathway?rno00640+298079+65183+64040+171142+24533+24534+29634",0.0006341032,7,350,33,7583,0.05854886,3.19784,"ALDH1B1//ALDH3A2//ALDH9A1//EHHADH//LDHA//LDHB//LDHC"]
["rno00053","Ascorbate and aldarate metabolism - Rattus norvegicus (rat)","http://www.genome.jp/kegg-bin/show_pathway?rno00053+298079+65183+64040+25106+83472+396551",0.001201355,6,350,27,7583,0.08319386000000001,2.9203289999999997,"ALDH1B1//ALDH3A2//ALDH9A1//RGN//UGDH//UGT1A3"]
["rno00010","Glycolysis / Gluconeogenesis - Rattus norvegicus (rat)","http://www.genome.jp/kegg-bin/show_pathway?rno00010+298079+65183+64040+114508+24533+24534+29634+362282+25741+24651",0.002679321,10,350,77,7583,0.1258167,2.571975,"ALDH1B1//ALDH3A2//ALDH9A1//FBP2//LDHA//LDHB//LDHC//PCK1//PFKL//PKLR"]
["rno04727","GABAergic synapse - Rattus norvegicus (rat)","http://www.genome.jp/kegg-bin/show_pathway?rno04727+81636+24239+64670+81657+29689+79211+81667+64199+84587+29642+252919",0.002725271,11,350,90,7583,0.1258167,2.56459,"ADCY2//CACNA1C//GABARAPL2//GABBR1//GABRD//GABRG3//GNB2//GNG11//PLCL1//SLC38A2//SLC38A3"]
["rno04350","TGF-beta signaling pathway - Rattus norvegicus (rat)","http://www.genome.jp/kegg-bin/show_pathway?rno04350+83837+54244+25587+291023+83711+361178+54284+83840+29357+25717",0.004262689,10,350,82,7583,0.1520131,2.370316,"BAMBI//CREBBP//ID2//ID4//INHBE//MGC112830//PITX2//RPS6KB1//SMAD2//TGFB3"]
["rno05202","Transcriptional misregulation in cancer - Rattus norvegicus (rat)","http://www.genome.jp/kegg-bin/show_pathway?rno05202+295052+362110+24253+287765+116663+312777+78961+310669+171528+117056+79242+25587+24482+298894+304005+50662",0.004867154,16,350,169,7583,0.1520131,2.312725,"CCNA1//CDK9//CEBPB//DDX5//DUSP6//ETV6//GOLPH3//GOLPH3L//GZMB//H3F3B//HPGD//ID2//IGF1//MYCN//NFKBIZ//RUNX1"]
["rno04630","Jak-STAT signaling pathway - Rattus norvegicus (rat)","http://www.genome.jp/kegg-bin/show_pathway?rno04630+54244+25325+171040+252963+116562+308977+444986+155140+170819+25205+306141+288774+25126+54314",0.005761247000000001,14,350,142,7583,0.1520131,2.239483,"CREBBP//IL10//IL11//IL13RA1//IL2//IL21R//IL22RA2//IL23A//IL24//IL6ST//SPRY2//STAT2//STAT5B//TPO"]
["rno00340","Histidine metabolism - Rattus norvegicus (rat)","http://www.genome.jp/kegg-bin/show_pathway?rno00340+298079+65183+64040+307212+290564",0.006004349,5,350,26,7583,0.1520131,2.221534,"ALDH1B1//ALDH3A2//ALDH9A1//CNDP1//METTL6"]
["rno05323","Rheumatoid arthritis - Rattus norvegicus (rat)","http://www.genome.jp/kegg-bin/show_pathway?rno05323+297566+29538+29175+25464+171040+155140+309684+294269+294270+25717",0.006506678,10,350,87,7583,0.1520131,2.186641,"ATP6V1E1//CCL20//CTSK//ICAM1//IL11//IL23A//ITGB2//RT1-DA//RT1-DB1//TGFB3"]
["rno05321","Inflammatory bowel disease (IBD) - Rattus norvegicus (rat)","http://www.genome.jp/kegg-bin/show_pathway?rno05321+25325+116562+308977+155140+294269+294270+29357+25717",0.006585404,8,350,61,7583,0.1520131,2.181418,"IL10//IL2//IL21R//IL23A//RT1-DA//RT1-DB1//SMAD2//TGFB3"]
["rno04060","Cytokine-cytokine receptor interaction - Rattus norvegicus (rat)","http://www.genome.jp/kegg-bin/show_pathway?rno04060+29397+29538+288593+57301+84475+25325+171040+252963+116562+308977+444986+155140+170819+25205+83711+60427+25717+302965+54314+114111",0.007758692,20,350,241,7583,0.16531980000000002,2.110211,"CCL11//CCL20//CCL24//CCR1//CXCR3//IL10//IL11//IL13RA1//IL2//IL21R//IL22RA2//IL23A//IL24//IL6ST//INHBE//KITLG//TGFB3//TNFRSF12A//TPO//VEGFC"]
["rno01212","Fatty acid metabolism - Rattus norvegicus (rat)","http://www.genome.jp/kegg-bin/show_pathway?rno01212+83522+113976+171142+171402+84575+64669+246074",0.009374139,7,350,52,7583,0.1787657,2.028069,"ACOX3//ACSL4//EHHADH//ELOVL6//FADS1//OLAH//SCD1"]
["rno05310","Asthma - Rattus norvegicus (rat)","http://www.genome.jp/kegg-bin/show_pathway?rno05310+29397+25325+25316+294269+294270",0.009680451,5,350,29,7583,0.1787657,2.014104,"CCL11//IL10//MS4A2//RT1-DA//RT1-DB1"]
["rno05150","Staphylococcus aureus infection - Rattus norvegicus (rat)","http://www.genome.jp/kegg-bin/show_pathway?rno05150+155012+25464+25325+309684+58949+294269+294270",0.01147401,7,350,54,7583,0.1986438,1.940285,"CFH//ICAM1//IL10//ITGB2//PTAFR//RT1-DA//RT1-DB1"]
["rno05211","Renal cell carcinoma - Rattus norvegicus (rat)","http://www.genome.jp/kegg-bin/show_pathway?rno05211+54244+24356+29560+29432+24703+295347+24827+25717",0.01251684,8,350,68,7583,0.20395080000000002,1.9025050000000001,"CREBBP//ETS1//HIF1A//PAK2//RAF1//RAP1A//TGFA//TGFB3"]
["rno04142","Lysosome - Rattus norvegicus (rat)","http://www.genome.jp/kegg-bin/show_pathway?rno04142+29663+83800+54241+64529+25423+29175+282838+294673+25151+303801+298875+25524",0.01403454,12,350,127,7583,0.21381660000000002,1.852802,"AP1B1//CLTA//CLTC//CTSB//CTSC//CTSK//GM2A//HEXB//IGF2R//LAMP3//LAPTM4A//PSAP"]
["rno00410","beta-Alanine metabolism - Rattus norvegicus (rat)","http://www.genome.jp/kegg-bin/show_pathway?rno00410+298079+65183+64040+307212+171142",0.014666120000000001,5,350,32,7583,0.21381660000000002,1.833685,"ALDH1B1//ALDH3A2//ALDH9A1//CNDP1//EHHADH"]
["rno04062","Chemokine signaling pathway - Rattus norvegicus (rat)","http://www.genome.jp/kegg-bin/show_pathway?rno04062+81636+29397+29538+288593+57301+84475+81667+64199+25734+25031+170538+24703+295347+288774+25126",0.01736657,15,350,178,7583,0.2404872,1.760286,"ADCY2//CCL11//CCL20//CCL24//CCR1//CXCR3//GNB2//GNG11//HCK//PLCB4//PRKCD//RAF1//RAP1A//STAT2//STAT5B"]
["rno00071","Fatty acid degradation - Rattus norvegicus (rat)","http://www.genome.jp/kegg-bin/show_pathway?rno00071+83522+113976+298079+65183+64040+171142",0.01823188,6,350,46,7583,0.2404872,1.739169,"ACOX3//ACSL4//ALDH1B1//ALDH3A2//ALDH9A1//EHHADH"]
["rno05152","Tuberculosis - Rattus norvegicus (rat)","http://www.genome.jp/kegg-bin/show_pathway?rno05152+24253+54244+63868+25325+155140+362418+309684+29469+25336+171378+24703+294269+294270+308589+25717",0.019917280000000002,15,350,181,7583,0.2507767,1.70077,"CEBPB//CREBBP//HSPD1//IL10//IL23A//IRAK2//ITGB2//LBP//NFYB//PPP3CC//RAF1//RT1-DA//RT1-DB1//SPHK2//TGFB3"]
["rno00592","alpha-Linolenic acid metabolism - Rattus norvegicus (rat)","http://www.genome.jp/kegg-bin/show_pathway?rno00592+83522+29359+298579+24653",0.026177890000000002,4,350,25,7583,0.2984963,1.582065,"ACOX3//PLA2G10//PLA2G2D//PLA2G4A"]
["rno05166","HTLV-I infection - Rattus norvegicus (rat)","http://www.genome.jp/kegg-bin/show_pathway?rno05166+81636+366381+54244+24356+25445+25464+116562+309684+81710+25336+171378+294269+294270+25176+29357+25126+25717+83532+64566+282582+79426",0.02851884,21,350,292,7583,0.2984963,1.5448680000000001,"ADCY2//CDC26//CREBBP//ETS1//FOSL1//ICAM1//IL2//ITGB2//MSX1//NFYB//PPP3CC//RT1-DA//RT1-DB1//SLC25A5//SMAD2//STAT5B//TGFB3//VDAC3//WNT5A//WNT5B//ZFP36"]
["rno00604","Glycosphingolipid biosynthesis - ganglio series - Rattus norvegicus (rat)","http://www.genome.jp/kegg-bin/show_pathway?rno00604+294673+64018+83505",0.02933813,3,350,15,7583,0.2984963,1.532568,"HEXB//SLC33A1//ST3GAL5"]
["rno04720","Long-term potentiation - Rattus norvegicus (rat)","http://www.genome.jp/kegg-bin/show_pathway?rno04720+24239+54244+24409+25031+171378+24703+295347",0.02938471,7,350,65,7583,0.2984963,1.531879,"CACNA1C//CREBBP//GRIN2A//PLCB4//PPP3CC//RAF1//RAP1A"]
["rno01040","Biosynthesis of unsaturated fatty acids - Rattus norvegicus (rat)","http://www.genome.jp/kegg-bin/show_pathway?rno01040+83522+171402+84575+246074",0.0298458,4,350,26,7583,0.2984963,1.5251169999999998,"ACOX3//ELOVL6//FADS1//SCD1"]
["rno04010","MAPK signaling pathway - Rattus norvegicus (rat)","http://www.genome.jp/kegg-bin/show_pathway?rno04010+24225+24239+116600+25297+116663+25112+60460+24518+116596+81737+25054+29432+24653+24666+24667+171378+24703+295347+25717",0.03138884,19,350,260,7583,0.2984963,1.503225,"BDNF//CACNA1C//CACNB2//CACNB3//DUSP6//GADD45A//HSPA2//JUND//MAP3K8//NTF3//NTRK2//PAK2//PLA2G4A//PPM1A//PPM1B//PPP3CC//RAF1//RAP1A//TGFB3"]
["rno00280","Valine, leucine and isoleucine degradation - Rattus norvegicus (rat)","http://www.genome.jp/kegg-bin/show_pathway?rno00280+298079+65183+64040+171142+63938+29637",0.03151516,6,350,52,7583,0.2984963,1.50148,"ALDH1B1//ALDH3A2//ALDH9A1//EHHADH//HIBADH//HMGCS1"]
["rno04110","Cell cycle - Rattus norvegicus (rat)","http://www.genome.jp/kegg-bin/show_pathway?rno04110+295052+366381+54244+25112+361178+314949+29357+25717+308937+25577+25578",0.03232812,11,350,127,7583,0.2984963,1.49042,"CCNA1//CDC26//CREBBP//GADD45A//MGC112830//RAD21//SMAD2//TGFB3//WEE1//YWHAQ//YWHAZ"]
["rno00270","Cysteine and methionine metabolism - Rattus norvegicus (rat)","http://www.genome.jp/kegg-bin/show_pathway?rno00270+24962+24533+24534+29634+24551",0.03556475,5,350,40,7583,0.3141884,1.44898,"CTH//LDHA//LDHB//LDHC//MDH1"]
["rno00030","Pentose phosphate pathway - Rattus norvegicus (rat)","http://www.genome.jp/kegg-bin/show_pathway?rno00030+114508+25741+25106+64524",0.03804954,4,350,28,7583,0.3141884,1.419651,"FBP2//PFKL//RGN//TKT"]
["rno00512","Mucin type O-Glycan biosynthesis - Rattus norvegicus (rat)","http://www.genome.jp/kegg-bin/show_pathway?rno00512+311952+313878+83627+64043",0.03804954,4,350,28,7583,0.3141884,1.419651,"GALNT11//GALNT14//GALNT5//GCNT1"]
["rno04724","Glutamatergic synapse - Rattus norvegicus (rat)","http://www.genome.jp/kegg-bin/show_pathway?rno04724+81636+24239+81667+64199+24409+24653+25031+171378+29642+252919",0.03926016,10,350,115,7583,0.3141884,1.406048,"ADCY2//CACNA1C//GNB2//GNG11//GRIN2A//PLA2G4A//PLCB4//PPP3CC//SLC38A2//SLC38A3"]
["rno04270","Vascular smooth muscle contraction - Rattus norvegicus (rat)","http://www.genome.jp/kegg-bin/show_pathway?rno04270+81636+29316+24239+24323+114593+29359+298579+24653+25031+170538+24703",0.04112694,11,350,132,7583,0.3141884,1.385874,"ADCY2//ADORA2B//CACNA1C//EDN1//NPPC//PLA2G10//PLA2G2D//PLA2G4A//PLCB4//PRKCD//RAF1"]
["rno04664","Fc epsilon RI signaling pathway - Rattus norvegicus (rat)","http://www.genome.jp/kegg-bin/show_pathway?rno04664+54259+81511+155918+25316+24653+170538+24703",0.04170279,7,350,70,7583,0.3141884,1.379835,"INPP5D//LAT//LCP2//MS4A2//PLA2G4A//PRKCD//RAF1"]
["rno05144","Malaria - Rattus norvegicus (rat)","http://www.genome.jp/kegg-bin/show_pathway?rno05144+364837+25464+25325+309684+25216+25717",0.04318202,6,350,56,7583,0.3141884,1.364697,"GYPC//ICAM1//IL10//ITGB2//SDC1//TGFB3"]
["rno04066","HIF-1 signaling pathway - Rattus norvegicus (rat)","http://www.genome.jp/kegg-bin/show_pathway?rno04066+54244+24323+117045+29560+24482+24533+24640+54283+25741+83840",0.04337453,10,350,117,7583,0.3141884,1.362765,"CREBBP//EDN1//EIF4E//HIF1A//IGF1//LDHA//PFKFB2//PFKFB4//PFKL//RPS6KB1"]
["rno05410","Hypertrophic cardiomyopathy (HCM) - Rattus norvegicus (rat)","http://www.genome.jp/kegg-bin/show_pathway?rno05410+24239+116600+25297+24323+24482+81008+29557+25717",0.04423592,8,350,86,7583,0.3141884,1.354225,"CACNA1C//CACNB2//CACNB3//EDN1//IGF1//ITGA7//MYH7//TGFB3"]
["rno04976","Bile secretion - Rattus norvegicus (rat)","http://www.genome.jp/kegg-bin/show_pathway?rno04976+114628+81636+25428+60351+24777+29500+80900",0.04744511,7,350,72,7583,0.315286,1.323809,"ABCG5//ADCY2//CYP7A1//NR1H4//SLC10A1//SLC10A2//SLCO1A5"]
["rno05414","Dilated cardiomyopathy - Rattus norvegicus (rat)","http://www.genome.jp/kegg-bin/show_pathway?rno05414+81636+24239+116600+25297+24482+81008+29557+25717",0.04956137,8,350,88,7583,0.315286,1.304857,"ADCY2//CACNA1C//CACNB2//CACNB3//IGF1//ITGA7//MYH7//TGFB3"]
["rno00330","Arginine and proline metabolism - Rattus norvegicus (rat)","http://www.genome.jp/kegg-bin/show_pathway?rno00330+298079+65183+64040+29215+307212+64313",0.049909590000000004,6,350,58,7583,0.315286,1.301816,"ALDH1B1//ALDH3A2//ALDH9A1//ARG2//CNDP1//OAT"]